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Vascular Differentiation
Co-sponsored by European Vascular Biology Organization
Making endothelial and epithelial tubes
Ondine Cleaver, UT Southwestern Medical Center
Endothelial cell specification
Didier Stainier, Max Planck Institute for Heart & Lung Research

Vascular Aging
Co-sponsored by the Japanese Vascular Biology and Medicine Organization
Vessel-tissue interactions during aging
Anjali Kusumbe, University of Oxford
Targeting senescent cells for the treatment of cardiovascular disease
Tohru Minamino, Juntendo University

Lymphangiogenesis
Co-sponsored by Australian Vascular Biology Society
Dissecting the mechanisms by which lymphatic endothelial cell identity is transcriptionally programmed
Natasha Harvey, University of South Australia
The specification of the lymphatic vascular lineage and the role of Prox1 in zebrafish
Benjamin Hogan, Peter MacCallum Cancer Centre 

Stem Cells
Regulation of endothelial cell specialization
Karen Hirschi, University of Virginia
Adaptable and hemodynamic human endothelial cells for tissue-specific organogenesis
Shahin Rafii, Weill Cornell Medical College

Vascular Cell Differentiation and Plasticity
Do cells with different developmental trajectories remember their history?
Kristy Red-Horse, Stanford University
Novel Regulatory Functions of GPCRs in Vascular Growth and Development
Kathleen Caron, University of North Carolina, Chapel Hill

Epigenetic Regulation
What chromatin remodelers can teach us about vascular development and integrity
Courtney Griffin, Oklahoma Medical Research Foundation
Physiologic and Pathologic Changes in Chromatin Remodeling in Vascular Cells
Marlene Rabinovitch, Stanford University

Impact of Microvascular Aging in Development and Progression of Cardiovascular Pathology
Sponsored by the Microcirculatory Society
Restoring coronary microvascular dilation to flow in old age – is NO necessary for a comeback
Amanda Joe LeBlanc, University of Louisville
Energetics of mouse brain microvessels: Impact of age and sex
Prasad Katakam, Tulane University 

Vascular Plasticity
Sponsored by the European Vascular Biology Organization
Co-sponsored by the British Microcirculation and Vascular Biology Society

Senescence and Vascular Smooth Muscle Cell Plasticity
Martin Bennett, University of Cambridge
Vascular plasticity in the growing, aging and regenerating skeletal system
Ralf Adams, Max Planck Institute for Molecular Biomedicine

Vascular Heterogeneity
Sponsored by European Vascular Biology Organization
Vascular heterogeneity during organ growth and regeneration
Karina Yaniv, Weizmann Institute of Science
Lymphatic endothelial heterogeneity in development and disease
Taija Makinen, Uppsala University

Organ Crosstalk
Co-sponsored by Korean Society for Vascular Biology and Medicine
Aging, stress and systemic inflammation: Can the endothelium be the master regulator of it all via RNA decay proteins?
Luisa Iruela-Arispe, Northwestern University
Endothelial metabolism in the muscle microenvironment
Katrien de Bock, ETH Zürich (EVBO Award Lecturer)

Blood Brain Barrier
Co-sponsored by Societe Française d’Angiogenese
Mechanisms of blood-brain barrier damage and pathological angiogenesis in neuroinflammation
Dritan Agalliu, Columbia University
The Neuro-vascular interactions in the CNS
Chenghua Gu, Harvard Medical School

Neurovascular Crosstalk
Co-sponsored by European Vascular Biology Organization
Crosstalk between blood vessels and neural cells in the central nervous system
Carmen Ruiz de Almodovar, University of Bonn
Unexpected vascular findings at the brain borders
Jonathan Kipnis, Washington University in St. Louis

Lymphatics
Co-sponsored by European Vascular Biology Organization
Lymphoangiocrine factors in organ repair
Guillermo Oliver, Northwestern University
Manipulation of meningeal lymphatics in CNS disease
Kari Alitalo, University of Helsinki

Smooth Muscle Cells
TBD
Rescuing cerebral blood flow deficits in small vessel disease of the brain
Mark Nelson, University of Vermont

Endothelial Organ Heterogeneity and Stem Cells 
Co-sponsored by the Japanese Vascular Biology and Medicine Organization
Vascular heterogeneity in respiratory organs
Gou-Young Koh, IBS/KAIST
Development and senescence of resident vascular endothelial stem cells
Nobuyuki Takakura, Osaka University

Mechanotransduction
Co-sponsored by the American Society for Investigative Pathology
Mechanotransduction in endothelial cells
Ellie Tzima, University of Oxford
Precision vascular nanomedicine targeting novel endothelial mechano-sensing mechanisms
Yun Fang, University of Chicago

Cell-Cell Interactions
Co-sponsored by Korean Society for Vascular Biology and Medicine
Bioactive lipid regulation of vascular and innate immune systems
Tim Hla, Boston Children's Hospital
Tie'ing Up Loose Ends in the Vasculature
Susan Quaggin, Northwestern University

Vascular Cell-Blood Interaction
Co-sponsored by Australian Vascular Biology Society
Novel mechanisms for therapeutic angiogenesis
Napoleone Ferrara, University of California, San Diego
Pathogenic vascular signaling mechanisms
Mark Kahn, University of Pennsylvania

Vascular Cell-Matrix Interactions
Co-sponsored by the Japanese Vascular Biology and Medicine Organization
Novel mouse model of familial thoracic aortic dissection
Hiromi Yanagisawa, University of Tsukuba
Smooth muscle cell transdifferentiation in response to matrix stiffening
Michelle Bendeck, University of Toronto

Angiogenesis and Vascular Remodeling
Sponsored by the Japanese Vascular Biology and Medicine Organization
Blood flow-driven intraluminal pressure mediates wound angiogenesis by regulating the TOCA family of F-BAR proteins
Shigetomo Fukuhara, Nippon Medical School
Vascular patterning in the skeletal system
Yoshiaki Kubota, Keio University
Tumor endothelial cells induce metastasis by disrupting immune environment
Kyoko Hida, Hokkaido University
Roles of ANGPTL2 in physiology and pathophysiology
Yuichi Oike, Kumamoto University

Leukocyte Transendothelial Migration
Sponsored by the American Society for Investigative Pathology
Cellular pathways of T-cell diapedesis across vascular and non-vascular brain barriers in vitro and in vivo
Britta Engelhardt, University of Bern
How the endothelium allows leukocytes to cross: Secrets Revealed by high-end microscopy
Jaap van Buul, Sanquin Research and Landsteiner Laboratory

 

Strategies to Understand and Treat COVID-19
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases
Alex Arenas, Universitat Rovira i Virgili
Wnt pathways in pulmonary vascular health and disease
Vinicio de Jesus Perez, Stanford University

Heterogeneity of Vascular and Immune Cells
Application of dual recombinases-mediated genetic system in endothelial cell study
Bin Zhou, Chinese Academy of Science
Cellular Reprogramming Approaches to Cardiovascular Disease
Deepak Srivastava, Gladstone Institutes

New -omics Approaches
Multiomics Approaches for Systems Biology in Human Cardiovascular Disease
Manuel Mayr, King’s College London
A multi-omics approach to dissect the multi-layer networks of cardiovascular disease: from metabolites to proteins
Sasha Singh, Brigham and Women's Hospital, HMS

Systems Approach to Target Discovery
Co-sponsored by the Japanese Vascular Biology and Medicine Organization
Systems approach to target discovery for inflammatory vascular disease: a focus on macrophages
Masanori Aikawa, Brigham and Women's Hospital, HMS
Genetic Regulation of Vascular Smooth Muscle Cell Function
Mete Civelek, University of Virginia

Imaging and Computational Approaches
Unravelling vascular biology with multispectral single cell genetics
Rui Benedito, CNIC
Imaging neurovasculature at high spatiotemporal resolution
Na Ji, University of California, Berkeley

Bioengineering
Co-sponsored by International Society for Applied Cardiovascular Biology 
Engineered Microvascular Niches for Evaluation of Pericyte Form and Function
Anjelica Gonzalez, Yale University
Forces and adhesions: New insights in regulating endothelial function
Christopher Chen, Boston University

Innovative research on key molecule to regulate heart, blood, and vessel
Sponsored by The Korean Society of Cardiology
- October 14, 4:00-5:30 pm
Discovery of surface marker for cardiac progenitors from human iPSCs: role of Latrophillin2
Hyun-Jai Cho, Seoul National University
Cross-road of hematopoiesis and angiogenesis: role of Kai1 (CD82)
Yoo-Wook Kwon, Seoul National University

Revealing Vascular Biology through Omics Lenses
Sponsored by Chinese American Academy of Cardiology
Immunological signaling in inflammatory monocyte subsets in hyperhomocysteinemia, hyperlipidemia, T1DM and T2DM mice
Hong Wang, Temple University
Integrating 5-D light-field imaging with deep learning to elucidate cardiovascular morphogenesis
Tzung Hsiai, University of California, Los Angeles
Endothelial cell derived-VEGF signaling licenses the transition of non-committed cells toward an endothelial cell fate
Hong Chen, Harvard Medical School/Boston Children’s Hospital
PANDORA-seq unveils a hidden small non-coding RNA landscape associated with atherosclerosis development in LDL receptor-deficient mice
Changcheng Zhou, University of California, Riverside
Epigenetic Control of Smooth Muscle Cell Phenotypic Alterations in Aortic Aneurysm and Dissection
Ying Shen, Baylor College of Medicine
The class III phosphatidylinositol 3-kinase PIK3C3 is a master regulator for smooth muscle cell identity
Jiliang Zhou, Augusta University

Innovation of Gene Therapy Technology
Sponsored by Anges
HGF gene therapy
David G. Armstrong, University of Southern California
Molecular Mechanisms of AAA Disease
Philip Tsao, Stanford University
Gene Therapy and DNA Vaccine
Hironori Nakagami, Osaka University

Frontiers in Vascular Biology
Sponsored by Frontiers in Cardiovascular Medicine
TBD
Eugene C. Butcher, Stanford University School of Medicine
Publishing about lncRNAs Key points to be included in your manuscript: perspectives from editors and reviewers
Shizuka Uchida, Aalborg University
TBD
Cécile Oury, University of Liège

Tumor Biology
Co-sponsored by Societe Française d’Angiogenese

Vascular control of aging and metastasis
Hellmut Augustin, Heidelberg University
The tumor microenvironment and resistance to checkpoint blockade therapy in cancer
Rosemary Akhurst, University of California, San Francisco

Vascular-Immune Interface in Cancer
Co-sponsored by the American Society for Investigative Pathology
Effects of lymphatic activation on T cell plasticity in the tumor microenvironment
Melody A. Swartz, University of Chicago
High endothelial venules generate tumor-attacking T cell niches
Gabriele Bergers, VIB Center for Cancer Biology and KU Leuven

Vasculature in the Inflammatory Response 
Co-sponsored by the American Society for Investigative Pathology
Mechanisms that govern the dissemination of inflammatory signals from the intestine
Gwen Randolph, Washington University in St. Louis
Inflammation is a Double-Edged Sword. Anti-inflammatory Therapy Doesn't Have to Be
Bill Muller, Northwestern University

The Vasculature in Metabolic Disease
Co-sponsored by International Atherosclerosis Society
Vascular smooth muscle cAMP signaling in health and disease
Manuel Navedo, University of California, Davis
Current and Novel Therapies for Dyslipidemia and Prevention of Atherosclerosis
Raul Santos, University of Sao Paulo Medical School

Ocular and CNS Vascular Disease
Neutrophil arrest in brain capillaries causes cerebral blood flow deficits and contributes to memory impairment in Alzheimer's disease mouse model
Chris B. Schaffer, Cornell University
VEGF-B as a buffering system in angiogenesis
Xuri Li, Sun Yet-Sen University

Immune Vascular Crosstalk for Cancer Therapy
Supported by Eisai
Effect of angiogenesis inhibitor on tumor immune microenvironment
Yu Kato, Eisai
The vasculature as a target for therapy in glioblastoma
Anna Dimberg, Uppsala University

Myeloid Cells, Vasculature, and Cancer Progression
Sponsored by the American Society for Investigative Pathology
Tracking tumor cells through the vasculature: Who are the influencers of stemness, survival, and dormancy in the lung?
David Entenberg, Albert Einstein College of Medicine
Pro-angiogenic neutrophil reprograming in the tumor niche promotes tumor vascularization and growth
Ronen Sumagin, Northwestern University

Arterial Diseases
Co-sponsored by International Society for Applied Cardiovascular Biology 
New screening approaches to identify inhibitors for cardiovascular calcification
Elena Aikawa, Brigham and Women’s Hospital, HMS
ACTA2 pathogenic variants that predispose to childhood onset occlusive cerebrovascular disease uniquely disrupt a nuclear function of smooth muscle alpha-actin and lead to undifferentiated smooth muscle cells
Dianna Milewicz, UT Health Sciences Center at Houston

Vascular Malformations
Co-sponsored by European Vascular Biology Organization
Mechanisms of cerebral bleeding in the collagen IV disease
Anne Joutel, INSERM
From identification of somatic mutations to targeted therapies for vascular malformations
Miikka Vikkula, de Duve Institute, University of Louvain

AVMs and Somatic Vascular Malformations
Deciphering Molecular Mechanisms of Arteriovenous Malformation
Rong Wang, University of California, San Francisco
Somatic Activating KRAS Mutations in Brain Arteriovenous Malformations
Jason Fish, University of Toronto

Atherosclerosis
Co-sponsored by the American Society for Investigative Pathology
The role of efferocytosis in atherosclerosis
Nick Leeper, Stanford University
Protein sulfhydration and endothelial cell function
Ingrid Fleming, Johann Wolfgang Goethe University

Hypertension and Pulmonary Hypertension
Co-sponsored by The Microcirculatory Society
Vascular Mineralocorticoid Receptors in Cardiovascular Disease
Iris Jaffe, Tufts University
Vascular Diseases associated with the impairment of BMP signaling pathway
Akiko Hata, University of California, San Francisco

Inflammatory Vasculitis
Co-sponsored by The Microcirculatory Society
Immune Checkpoints in Vasculitis
Cornelia Weyand, Stanford University
Endothelial Immune cross talk
David Harrison, Vanderbilt University

Pathophysiology of Vascular Disease
Sponsored by the Japanese Vascular Biology and Medicine Organization
Roles of TGF-β signals during formation and maintenance of vascular systems
Tetsuro Watabe, Tokyo Medical and Dental University
Down syndrome and its trisomy gene set protect organ-specific vascular diseases with non-linearity
Takashi Minami, Kumamoto University
The molecular pathogenesis of pulmonary arterial hypertension via degradation of inflammatory cytokine mRNAs
Yoshikazu Nakaoka, National Cerebral and Cardiovascular Center
TBD
Masayuki Yoshida, Tokyo Medical and Dental University

The Vasculature in Health and Disease
Sponsored by Australian Vascular Biology Society
Deciphering the signalling cascades guiding vascular growth and integrity
Emma Gordon, University of Queensland
High salt diets contribute to atherosclerosis through a gut-bone axis
Andrew Murphy, Baker Heart and Diabetes Institute
Effective of stroke on pulmonary leukocytes and vasculature
Connie Wong, Monash University

New Therapeutics
Co-sponsored by British Microcirculation & Vascular Biology Society
DNA-based Gene Therapy
Ryuichi Morishita, Osaka University
TBD

Cardiovascular Regenerative Medicine
Stem Cells & Genomics for Precision Medicine
Joseph Wu, Stanford University
CAP1 is the pivotal molecule to bind Resistin or PCSK9, leading to inflammatory and metabolic diseases
Hyo-Soo Kim, Seoul National University

Translational Vascular Biology
Co-sponsored by Chinese American Academy of Cardiology
Notch function in the tumor microenvironment
Jan Kitajewski, University of Illinois at Chicago
Purinergic modulation of vascular L-type calcium channel Cav1.2
Madeline Nieves-Cintron, University of California, Davis

Lipoproteins in Vascular Disease
Co-sponsored by Chinese American Academy of Cardiology
HDL and Atherosclerosis: More than just cholesterol efflux
Edward A. Fisher, NYU Langone Health
The remnant lipoprotein hypothesis of diabetes-accelerated cardiovascular disease
Karin E. Bornfeldt, University of Washington

Dyslipidemia as Cardiovascular Risk
Co-sponsored by the International Atherosclerosis Society
Lipoprotein(a): Use of Stable Isotopes to Understand Protein Function
Gissette Reyes-Soffer, Columbia University
Targeting Triglyceride-rich Lipoproteins to Modify Cardiovascular Risk
Peter Libby, Brigham & Women's Hospital, HMS

Innovative research on mechanism for variant angina or diabetic cardiomyopathy
Sponsored by The Korean Society of Cardiology - October 15, 4:00-5:30 pm
Molecular mechanism of vasospastic angina: blood monocytes, iPSCs, and VSMCs
Han-Mo Yang, Seoul National University
Mechanism and therapeutic approach of diabetic cardiomyopathy
Sung Woo Cho, Inje University

Translational Approaches to Vascular Pathology and Regeneration
Sponsored by International Society for Applied Cardiovascular Biology
TBD
Yukiko Matsunaga, The University of Tokyo
Mechanisms Driving Osteogenesis in Cardiovascular Systems
Cynthia St. Hilaire, University of Pittsburgh
ECM Stiffness modulates EndoMT
Ngan Huang, Stanford University
Cell Based Vascular Regeneration
Sara Nunes de Vasconcelos, University of Toronto

Stem Cells and Regenerative Medicine
TBD
Hanna Mikkola, University of California, Los Angeles

Thursday -
Keynote Lecture: Molecular anatomy of the vasculature
Christer Betsholtz, Ph.D.
Professor of Vascular and Tumor Biology, Uppsala University and
Professor of Vascular Biology, Karolinska Institute

Inaugural Florence Sabin Award Presentation
Supported by Regeneron
Omolola Eniola-Adefeso, Ph.D.

Professor, Biomedical Engineering, Chemical Engineering and Macromolecular & Science Engineering
Associate Dean for Graduate & Professional Education
University of Michigan

Earl P. Benditt Award Lecture
Three Vignettes on Endothelial Plasticity, Vasculogenesis and Disruption
Joyce Bischoff, Harvard Medical School

Friday -
Keynote Lecture: Jeffrey Bluestone, Ph.D.
Traveling the Path to Immune Tolerance
A.W. and Mary Margaret Clausen Distinguished Professor of Metabolism and Endocrinology
Director, Hormone Research Institute in the Diabetes Center
University of California, San Francisco

Saturday -
Judah M Folkman Award in Vascular Biology Lecture
RNA based mechanism guiding endothelial cell behaviors
Stefania Nicoli, Yale University

Sunday -
Springer Junior Investigator Award Lecture
Recipient/Lecture to be determined

Stephen Schwartz Award for Outstanding Mentorship Presentation
Richard O. Hynes, Ph.D.
Daniel K. Ludwig Professor for Cancer Research, MIT
Intramural Faculty, Koch Institute
Investigator, Howard Hughes Medical Institute

Monday - 
Keynote Lecture:  Neurovascular crosstalks in the aging heart
Stefanie Dimmeler, Ph.D.
Professor of Experimental Medicine
Director of the Institute of Cardiovascular Regeneration
Center for Molecular Medicine, University of Frankfurt

General Session: New Signaling Mechanisms
Speakers -
Advancing a quantitative understanding of vasculature through VEGFR measurements
    Princess Imoukhuede, University of Washington
The Lung Lymphatics in Emphysema: Uncovering the Missing Link
    Hasina Outtz‐Reed, Weill Cornell Medical Center
Guidance of vascular barrier formation
    Anne Eichmann, Yale University
Vascular rejuvenation for healthier aging
    Eli Keshet, Hebrew University
The good and the bad of PIK3CA in endothelial cells
    Mariona Graupera, Josep Carreras Leukaemia Research Institute

6:30pmWelcome by Dr. Rong Wang, Chair of the IVBM 2022 Organizing Committee
6:35-7:35pmKeynote Lecture: Molecular anatomy of the vasculature
Christer Betsholtz, Ph.D.
Uppsala University
7:35-8:00pmPresentation of the Inaugural Florence Sabin Award
Omolola Eniola-Adefeso,Ph.D.
University of Michigan
8:00-9:00pmEarl P. Benditt Award Lecture: Three Vignettes on Endothelial Plasticity, Vasculogenesis and Disruption
Joyce Bischoff, Ph.D.
Boston Children's Hospital
9:00-10:00pmWelcome Reception
8:30-10:00amStem CellsSmooth Muscle CellsVascular Cell-Matrix InteractionsVascular MalformationsSystems Approach to Target Discovery

Translational Approaches to Vascular Pathology and Regeneration
Sponsored by the International Society for Applied Cardiovascular Biology

10:30am-12:00pmVascular AgingHeterogeneity of Vascular and Immune CellsCell-Cell InteractionsDyslipidemia as Cardiovascular RiskVascular-Immune Interface in Cancer

Frontiers in Vascular Biology
Sponsored by Frontiers in Cardiovascular Medicine

12:00-2:00pmPosters/Exhibits/Lunch
2:00pm-3:00pmKeynote Lecture:
Jeffrey Bluestone, Ph.D.
A.W. and Mary Margaret Clausen Distinguished Professor
Director, Hormone Research Institute
Diabetes Center
3:15-3:45pm Technical Showcases
3:45-5:15pmVascular DifferentiationBlood Brain Barrier
Co-sponsored by Societe Française d’Angiogenese
MechanotransductionArterial diseases  
4:00-5:30pm    Innovative Research on Key Molecule to Regulate Heart, Blood, and Vessel
Sponsored by The Korean Society of Cardiology
Revealing Vascular Biology through Omics Lenses
Sponsored by the Chinese American Academy of Cardiology
8:30-10:00amLymphangiogenesisAVMs and Somatic Vascular MalformationsTranslational Vascular BiologyOcular and CNS Vascular DiseaseBioengineeringMyeloid Cells, Vasculature, and Cancer Progression
Sponsored by the American Society for Investigative Pathology
10:30am-12:00pmVascular Cells Differentiation and PlasticityStrategies to Understand and Treat COVID-19Vascular Cell-Blood InteractionEndothelial Organ Heterogeneity and Stem CellsAtherosclerosisInnovation of Gene Therapy Technology Sponsored by AnGes
12:00-2:00pmPosters/Exhibits/Lunch
2:00-2:45pmJudah M Folkman Award in Vascular Biology Lecture: RNA based mechanisms guiding endothelial cell behaviors
Stefania Nicoli, Ph.D.
Yale School of Medicine
2:45-3:45pmSession to be determined
Sponsored by FujiFilm VisualSonics
Technical Showcase
3:45-5:15pmImaging and Computational ApproachesNeurovascular CrosstalkVascular PlasticityNew Therapeutics  
4:00-5:30pm    Innovative research on mechanism for variant angina or diabetic cardiomyopathy
Sponsored by The Korean Society of Cardiology 
Angiogenesis and Vascular Remodeling
Sponsored by the Japanese Vascular Biology and Medicine Organization
8:30-10:00amEpigenetic RegulationOrgan CrosstalkStem Cells and Renegerative MedicineTumor biology
Co-sponsored by Societe Française d’Angiogenese
Inflammatory VasculitisThe Vasculature in Health and Disease
Sponsored by the Australian Vascular Biology Society
10:30am-12:00pmLymphaticsCardiovascular Regenerative MedicineHypertension and Pulmonary HypertensionThe Vasculature in Metabolic DiseaseImmune-Vascular Crosstalk for Cancer Therapy

Leukocyte Transendothelial Migration
Sponsored by the American Society for Investigative Pathology

12:00-2:00pmPosters/Exhibits/Lunch
2:00pm-2:30pmSpringer Junior Investigator Award - 
Recipient to be determined
Based on abstracts by Junior Faculty - see details about applying
2:30pm-2:50pm

Presentation of the Stephen Schwartz Award to
Richard O. Hynes, Ph.D., MIT
Supported by Barbara Schwartz and Family

3:45-5:15pmNew -omics ApproachesVascular HeterogeneityVascular Inflammation and MicrobesLipoproteins in Vascular DiseaseImpact of Microvascular Aging in Development and Progression of Cardiovascular Pathology
Sponsored by the Microcirculatory Society
Pathophysiology of Vascular Disease
Sponsored by the Japanese Vascular Biology and Medicine Organization
8:00-9:00amKeynote Lecture: Neurovascular crosstalks in the aging heart
Stefanie Dimmeler, Ph.D.

University of Frankfurt
9:00-9:20amPresentation of the Travel Awards
BMVBS
JVBMO
NAVBO
more societies to be announced
9:20 - 9:40amPresentation by the 23rd IVBM Organizing Committee
Plan to visit Amsterdam in 2024
9:40-10:00amCoffee Break
10:00am-12:30pmNew Signaling Mechanisms
12:30-1:00pmConcluding Remarks